Novartis places $1B bet to push chronic lymphocytic leukemia (CLL) “Arzerra” into multiple sclerosis fray

Novartis places $1B bet to push  chronic lymphocytic leukemia (CLL) “Arzerra” into multiple sclerosis fray
Novartis' newly acquired Arzerra (ofatumumab) is up against some hefty competition in chronic lymphocytic leukemia (CLL). But the Swiss drugmaker has a plan for helping it achieve its sales potential.The Basel-based company is forking over as much as $1 billion to GlaxoSmithKline for the rights to the therapy as a multiple sclerosis treatment, it said Friday, including $300 million up front and $2...
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Gilead’s huge Sovaldi payoff yields a nice 23% pay hike for CEO

Gilead’s huge Sovaldi payoff yields a nice 23% pay hike for CEO
Gilead CEO John Martin No one would say Gilead Sciences CEO John Martin is hurting financially. For several years, he has collected annual compensation worth about $15 million. Not too shabby. And his stock gains since 2009 run into the hundreds of millions--yes, hundreds. But for a record-smashing year that vaulted his company into the ranks of the global top 10, Martin snared...
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Just where does AbbVie expect to find $7B in Imbruvica sales?

Just where does AbbVie expect to find $7B in Imbruvica sales?
For some industry watchers, AbbVie's ($ABBV) $21 billion pact to buy Imbruvica-maker Pharmacyclics ($PCYC) begged a lot of questions. For instance, after the company agreed to pay a price that steep--or "lofty," "staggering," and even "astronomical," to use analysts' words--how much would Imbruvica actually rack up in peak sales? And where would those sales come from? The Illinois p...
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Pharma’s ad spend vaults to $4.5B, with big spender Pfizer leading the way

Pharma’s ad spend vaults to $4.5B, with big spender Pfizer leading the way
Suspicions are confirmed: Pharma's spending on ads took a flying leap last year. By Kantar Media's numbers, direct-to-consumer ad spend hit $4.53 billion in 2014, up about 18% from $3.83 billion in 2013. That total beats the last several years handily, and for ad agencies and media outlets, marks a heartening recovery from the $3.47 billion trough in 2012. It's higher than the $4.17 billion spent...
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Novartis tackles immuno-oncology with a $750M Aduro deal for new R&D group

Novartis tackles immuno-oncology with a $750M Aduro deal for new R&D group
Dana Farber's Glenn Dranoff Novartis ($NVS), a leader among companies using the immune system to fight cancer, is betting up to $750 million on a promising therapeutic approach from Aduro Biotech, widening its arsenal of potential treatments. And the pharma giant coupled the deal with the announcement that it recruited Dana Farber's Glenn Dranoff to run a new in-house R&D gr...
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J&J, GSK in legal dust-up over Flonase allergy claims

J&J, GSK in legal dust-up over Flonase allergy claims
Spring is arriving, bringing with it pollen, allergy suffering, and litigation. With a $35 billion allergy market at stake, Johnson & Johnson and GlaxoSmithKline are duking it out over whose products do the best job of treating sniffling, sneezing and stuffy noses. J&J, whose McNeil Consumer Health sells Benadryl and Zyrtec, has sued GSK over advertising claims the British drugmaker made ...
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The top 15 pharma companies by 2014 revenue

The top 15 pharma companies by 2014 revenue
The names at the very top of our yearly list of biggest pharma companies are no surprise. Johnson & Johnson, Novartis, Roche and Pfizer have headed up the rankings for a couple of years now, albeit in varying order. But toward the bottom of the top 10, there's been a changing of the guard. For the first time, a biotech company has nudged aside one of the biggest Big Pharma names. Eli Lilly &a...
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Gilead to require proof of citizenship to buy Sovaldi in poor countries

Gilead to require proof of citizenship to buy Sovaldi in poor countries
Not long after Gilead Sciences' high-priced hep C superdrugs Sovaldi, and then combo drug Harvoni, hit the market, the California drugmaker struck deals with 11 generic drugmakers to make cut-rate versions available, and affordable, in 91 developing countries. But Gilead is not as generous as it might seem, Doctors Without Borders claims. It says Gilead has loaded up production agreements with nef...
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Gilead strikes Sovaldi price deal in Germany as it picks up speed in EU

Just days after Gilead COO John Milligan told investors to expect negotiations for its hep C franchise to unfold very quickly in Europe, Germany has said it has a deal to buy Sovaldi at €41,000 for a 12-week course. That is deeply discounted from the initial price of €56,500 with which the company started. The agreement was disclosed, Reuters reports, by GKV, the association of Germany's statutor...
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UAE forces pharma to cut prices on 280 meds as weak oil prices hit

Beginning next month, 26 international drugmakers will be earning less in the United Arab Emirates from many of their drugs. The companies negotiated a deal with the country's Ministry of Health in the latest reduction to drug prices, with one unfortunate product's price forced down by 55%. The drugmakers managed to persuade officials to strike 200 drugs from the price-reduction list, but 280 sti...
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